Dr. Steven P. Levine is a board-certified psychiatrist based in Princeton, NJ and internationally recognized for his contributions to advancements in mental health care. In 2010, dissatisfied with the current state of psychiatric medication treatment, Dr. Levine founded Ketamine Treatment Centers. This was the world’s first group of centers dedicated to rapidly-acting, cutting edge treatment of depression, anxiety, and pain disorders. This group of treatment centers has now changed its name to Actify, a network of care providers dedicated to changing the way depression and other mood disorders are treated. Actify stands as a light in the dark for struggling patients within a treatment system that is outdated, ineffective, and more focused on masking symptoms than creating cures. Actify helps people go from living with depression to living free from it.

Actify Provides
Ketamine Infusion Therapy
Spravato (nasal esketamine) for Depression
TMS for Depression
Ketamine for Bipolar Disorder
Ketamine for Anxiety
Ketamine for PTSD

Education and Medical Training

Fellowship:  Memorial Sloan-Kettering Cancer Center and New York Presbyterian Hospital – Weill Cornell Medical Center, New York, NY, Psychosomatic Medicine/Psycho-Oncology

Residency:  New York Presbyterian Hospital – Weill Cornell Medical Center, New York, NY, Psychiatry

Doctor of Medicine:  Tulane University School of Medicine, MD, 4 year academic scholarship

Undergraduate Degree:  The Johns Hopkins University, BA, with Honors, Phi Beta Kappa

Professional Activities

Ketamine Treatment Centers , Founder, President and CEO

Actify Neurotherapies, Founder and Chief Medical Officer

Licensure and Certifications

  • Board Certified, American Board of Psychiatry and Neurology
  • New Jersey License
  • Maryland License
  • Colorado License
  • North Carolina License
  • Florida License
  • New York License
  • Pennsylvania License
  • California License

Professional Memberships

American Board of Psychiatry and Neurology, Diplomate, 2008

American Society of Ketamine Physicians, Vice President

American Society of Clinical Psychopharmacology

International College of Neuropsychopharmacology

American Psychiatric Association

New Jersey Psychiatric Association


  • New Jersey Monthly, Top Doc, 2014, 2016-2019
  • SJ Magazine, Top Doc, 2013
  • Weill/Cornell Alumni Association, Resident Teaching Award, 2007
  • Tulane University School of Medicine, Academic scholarship, 1999-2003
  • The Johns Hopkins University, Phi Beta Kappa, 1999

Institutional/Hospital Affiliations

  • Trinity Counseling Service, Princeton, NJ, Board of Trustees
  • Rutgers Robert Wood Johnson Medical School, Clinical Assistant Professor

Research and Publications

Peer Reviewed Articles (Abstracts and popular press not listed)

Wilkinson, S. T., Toprak, M., Turner, M. S., Levine, S. P., Katz, R. B., & Sanacora, G. (2017). A Survey of the Clinical, Off-Label Use of Ketamine as a Treatment for Psychiatric Disorders. American Journal of Psychiatry, 174(7), 695-696.

Levine, S. P. (2018). The Rise of Ketamine in Clinical Practice. Psychiatric Annals, 48(4), 167-168.

Dougherty, J. W., Ettensohn, M. F., & Levine, S. P. (2018). Beyond Depression: Ketamine and Glutamatergic Agents for PTSD, OCD, and Other Potential Applications. Psychiatric Annals, 48(4), 184-188.

Dugar, A., Ettensohn, M. F., & Levine, S. P. (2018). Ketamine and Its Pharmacologic Profile in Psychiatric Disorders. PSYCHIATRIC ANNALS, 48(4), 171.

Klise, A., Lerner, B., Ettensohn, M. F., & Levine, S. P. (2018). Ketamine Treatment for Mood Disorders. Psychiatric Annals, 48(4), 175-179.

Barnea ER, Simon J, Levine SP, Coulam CB, Taliadouros GS, Leavis PC. Progress in characterization of preimplantation factor in embryo cultures and in vivo. American Journal of Reproductive Immunology 1999; Aug; 42(2): 95-9.

Scientific Poster Presentation

Levine SP, Frischtak P. Retrospective Chart Analysis of 740 Patients Treated with IV Ketamine. Poster presented at: International College of Neuropsychopharmacology (CINP) Thematic Meeting; July 20-22, 2017; Prague, Czech Republic.

Levine SP, Frischtak P. Retrospective Chart Analysis of 740 Patients Treated with IV Ketamine. Poster presented at: NNDC Annual Conference; September 25-27, 2017;  Ann Arbor, MI.

Book Chapters

Levine SP (chapter author).  The IV Ketamine Experience.  In The Ketamine Papers.  Editor:  Philip Wolfson.  MAPS Publications.  2016.

Barnea ER, Levine SP (chapter authors). Maternal Immune Response in Trophoblast, GTD, and Cancer. Cancer and Autoimmunity. New York, NY: Elsevier Science, Ltd. 1999; Editors:  Yehudah Schoenfeld and Eric Gershwin.

Levine SP. Comprehensive Care in Schizophrenia. In The Approach to the Psychiatric Patient. Barnhill JW, editor. American Psychiatric Association Press. 2008, updated for 2nd edition, 2018.

Lectures (recent selected)

Grand Rounds – Albert Einstein College of Medicine, Jacobi Medical Center, “Data from 25,000 Ketamine Infusions for 2,500 Patients”, 3/28/18.

Oxford University, Ketamine and Related Compounds for Psychiatric Disorders, invited speaker, “Data from 25,000 Ketamine Infusions for 2,500 Patients”, 3/21/18

KRIYA conference, Hillsborough, CA, 11/4/17

The Permanente Medical Group 2017 conference:  Ketamine: Transforming the Treatment of Depression, “The Awe Experience of Ketamine…So What?”, April 28-29, 2017

Grand Rounds – University of Maryland School of Medicine, 11/17/16

Grand Rounds- Memorial Sloan Kettering Cancer Center, “Ketamine at the End of Life”, 6/24/16

Icahn School of Medicine at Mt. Sinai, invited speaker, Mood and Anxiety Disorders Seminar, 4/6/16

The Permanente Medical Group, Kaiser Permanente Ketamine Infusion Conference, invited speaker, “Bridging the Evidence-Based and the Anecdotal in an Outpatient Ketamine Clinic”, 3/11/16

Grand Rounds – Rutgers Robert Wood Johnson Medical School, “5 Years and 500 patients:  Thoughts on the use of Ketamine for Depression,  2/11/16

Banbury Center, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, invited speaker for the Therapeutic Use of Ketamine for Treating Severe Depression: Risks and Potential conference, September 20-22, 2015

Grand Rounds – Princeton House, University Medical Center of Princeton, “Beyond SSRIs:  Strategies for Treatment Refractory Mood Disorders”, 12/9/13,

Grand Rounds – State University of New York – Buffalo, “Ketamine Infusion Therapy for Depression”, 4/19/13

Grand Rounds – Princeton House, University Medical Center of Princeton, “Ketamine Infusion Therapy for Depression”, 1/9/12